Stanford’s Sapolsky On Depression in U.S. (Full Lecture)

100 thoughts on “Stanford’s Sapolsky On Depression in U.S. (Full Lecture)

  1. and the reason Standford isn't creating graduates who can quilty cure depression- THEY HAVE NO IDEA WHAT DEPRESSION IS YET. This is an education system that can only profit off causing problems, they are not in the business of solving problems, no profits in solutions, only profits are found in causing problems people react to so you can sell them drugs for a lifetime.

  2. This is excellent, compassionate, informative lecture. Thank you for posting this! I have heard Dr. Sapolsky refer to people suffering from this diagnosis as both "depressives" and "people who have depression". In the larger context of Mental Health, and stigma and misinformation regarding mental health diagnoses (which this lecture is actively working to remedy in my opinion), terms like depressives, or saying someone IS a bi-polar (for example), is incorrect and does not recognize the personhood of the individual as paramount to the diagnosis. I challenge myself everyday, and now all who read this comment, to consciously use language that respects and recognizes the personhood in every individual (regardless of a mental health diagnosis or not), but in particular when speaking about, and too individuals with these diagnoses. We are not depressives, or bi-polars, or schizophrenics, or psychos, we are PEOPLE who have depression, PEOPLE who have bi-polar, PEOPLE who have schizoaffective disorder. You may not know the profound influence you have on someone when you address them as an individual, and NOT their diagnosis (or disability) but it is tangible, and sometimes life saving.

  3. I have had an Rx and forced myself to watch SAD content visually, sad movies, as stimulus and can confirm it made no effect on making me physically sad. The realization of its effect of shuting down the emotion, and forcing stimulus to not get an expected result of sad. I felt to be abnormal, incomplete. I discontinued use because of that reason. I want to know more, do you ship the required books in the sylabus to Canada?

  4. 8:48 I've been fighting the psychomotor retardation for 2 years now, I can't get myself to eat, I can't get myself to leave the bed, I can't even brush my teeth or shower. I been stuck in this loop trying to get routines working but they never stick, It might work for a few days a week at max, then all of the sudden the depression just pulls me straight back down and I go into this "psychosis" again. I was on SSRI for 4 years but quit them cold turkey about 1.5 years ago. I feel like I know myself better by staying of the meds but I also feel like this psychomotor retardation has crippled me way harder off the meds. This constant loop of psychomotor retardation > good week trying to get routines > fall back into depression has gotten me feeling exhausted after 2 years. I don't feel sadness or pain anymore, I just want this to stop.

  5. Thank you, Mr Sapolsky. I suffer from depression for about 15 years. This video helped my friends begin to understand why I'm often such an indecisive whiny bitch.

  6. Every day is a mammoth struggle and is made infinitely worse by the fact that the people I love can not see it. Thank you for this video. I don't feel crazy anymore.

  7. This condition is debilitating, so how do these genes still exist? Why does no one ever talk about irritability as a symptom?

  8. The ancient history of depression during modern times. The reason, in fact, so many people suffer. Depression remains untreated at the root cause of it.

  9. If ever you've been confused by the mechanism of action of the various classes of antidepressants, then this is a must-view. An elegant and enlightening lecture.

  10. This one hour lecture helped me more with my depression than years of counseling. Once I understood where my depression originated, I was able to find a step by step coping process. I can’t thank Dr. Spolasky enough for helping me change my perspective of my disease. I loss my mother a year ago, I return to Dr Spolskys lectures and it makes me appreciate how wonderful we are as humans and the beautiful mechanisms of our anatomy and physiology. I think his lectures have made me more intelligent in the process.

  11. Every single thing he said is something I have completely failed to communicate to multiple doctors, psychiatrists, police officers, social workers, friends, family. This disease has only gotten worse and spread to more Americans. This is truly remarkable and terrifying.

  12. These videos attached are very good….talking about narcissistic parents and how the reverse parenting takes away the sense of agency and locus of control becoming strictly external for childhood survival necessity leading to poor cognitive development…
    https://youtu.be/SfypfTi1UnA

    https://youtu.be/THl8L4SHAvA

  13. I get severe depression when I eat milk, eggs, turkey, sunflower seeds, and sucralose. There are physical symptoms too: severe back pains (sunflower seeds), burping (with sucralose), asthma attacks (eggs).
    I ate sunflower seeds a while back and actually felt guilty just out of the blue! It was so weird, but these depressions are outside my normal thoughts. The sucralose depression does piggy back on my thoughts, however. I've never had reactive depression, but have known people who have had it.

  14. If you don't say what people can do to get out of depression, what good is giving a speech about it? Go to Dr. Neil Nedley. He helps people overcome depression.

  15. I think that if you manage to "come out the other end" you did NOT have depression, not a "serious" one.
    Real pain, is ONLY when it lasts forever, if its temporary its not actually there as you will have a way to heal it and eventually "forget" it or replace it with good feelings.
    Of course I'm no doctor so that's just my useless 2 cents, but as someone who will suffer literally forever until he dies I find it really annoying when people say that it's even POSSIBLE to "come out the other end" because sometimes it is not possible.

  16. This sheer complexity and half of the talk is just about getting rid of common misconceptions. Interestingly, if you are invested in psychiatric disorders, you have to do both, look how the condition can be eleviated and at the same time tell the public it is actually a thing. To be quite frank, in absence of information, I would easily think you can change depression via the right way of thinking. But this is only one piece of the puzzle with an effectiveness which depends heavily on a whole lot of other conditions on a lot of levels, both endogenous and exogenous. Sure as hell, listening to this one time is not enough.

  17. It is addiction of psychiatrists to betray, to torture animals, to rape and to be brutal to animals and humanbeings.
    IT is war and the violence outside is that of rapists, if torturers of animals and of brutals, which are as disgusting as this mob of primitivs, of drugaddicts and of sadists, who porn and robb, terrorise and torture animals out of their way and yes, they do this to all those, who protest the real sadists, the real drugaddicts, the real torturers of animals, the real rapists and the satanists outside, for Real satanists are cowards in cruelty and organised violence and even rape and prostitution, which Real criminels and torturers of animals do, real rapists and real torturers of animals,they laugh about cruelty, about sadistic violence and even about rape and cruel violence to animals and humanbeings.
    They laugh about sadistic cruelty to animals, the even organise it, by ripping off the organs, they organise this to children also, laugh about sadistic cruelty and sadistic violence to them.
    Psychiatrists are torturers of animals, which laugh about cruelty, brutality and terror and sadistic cruelty to animals and not but animals, they laugh about brutal violence by mob, for All those, who are psychiatrists are torturers of animals also.

  18. Do "slut" hunters love cats? NO, Not at all.
    Do dog fanatics love cats? NO, Not at all.
    Do sadists, Islamists and psychiatrists engaged in torture of animals, do love animals?
    Not at all.
    Do rapists love animals or cats?
    NO, Not at all.
    Do narcissists love animals or children?
    NO, they, use and abuse them as their servants.
    Do torturers of animals as are psychiatrists love animals?
    NO, Not at all.
    Do racists love animals or children, no not at all, they cripple, they damage, they shoot onto them, as they are used to be brutal, to be evil and sadistic, mean and violent and therefor murder all those, which are feeling empathy to those, which they crippled in full intent do so, which is fun to sadists as torturers of animals, as are psychiatrists, as it is a sadistic fun to torturers of animals, which study, how to torture them to death and how to use and to abuse animals and even children to be studied, chased and hunted until they are dead, or kill themselves in despair,for the raptorraces already won over. In the planned violence of war and in the planned overkill, which it will be by the uttermost evil and insane, which are as cruel as are scientists in torture of animals and humanbeings also, keeping them to the raptorraces in a huerachy and a System, which is planned to kill the links, the "sluts", which at least have empathy to the damaged and crippled in full intent to do so,which sadists are used to laugh about in organised cruelty and terror, which is this perverted war about food and drugs and in neglect to the terror, which this, war is to animals and children, which get abused to this war, which is war by the torturers of animals, as are psychiatrists.

  19. I absolutely need to accomplish something that everybody will remember me for, to make a lasting contribution to humanity,
    even if I am not always right, like Sigmund Freud before I die.

  20. Looks like I have non-depression depression then. I get up relatively late, eat more when I'm stressed, have up days and down days, can enjoy sun rises and sunsets. I've forgotten what other things he said cos i watched the video yesterday.

  21. In-short this video has told me that we are absolutely fucked considering there are so many different factors at play causing this condition. So yeah, embrace the void fellas.

  22. Depression and loneliness are easily confused. Brain imaging shows that they are not the same thing. Many people tell their doctor that they are depressed, when really they are lonely. That is why anti-depressants don't work for them. And then, their doctor wonders why. It is because the patient misrepresented loneliness as depression; and so, of course, antidepressants are ineffective.

  23. Anyone know if there is a better version of this lecture posted online somewhere? I want to share it with a friend but they wont be able to understand what he's saying over the coughing, laughing, background noise.

    I believe he filmed his lecture Stanford series after this, but I don't see an episode called Depression in the listing.

  24. Thank you for offering your class instructions with us.

    I am 68 years old & I was told that my chronic depression & PTSD were developed due to childhood trauma. I am glad to hear your more biological explanation.

    I have, over a lifetime, developed coping mechanisms to manage my depression & anxiety. I still take two meds for depression. But stress management, nutrition, & good sleep have long term improvement.

  25. i disagree that depression is mostly a biological disorder. thats most often not the case. its more starts by psychology that can affect the whole body(biology)

  26. Depression is just as socioeconomic as it is biological. Just a friendly reminder to the reductionists out there.

  27. The moment you guys associate a laugh with actual bullying is the day you reveal that you don’t really understand how nuanced emotions can be

  28. Between 2 ferns. Entities are real and have been recorder multiple times. They can be good or bad and is karma bound to that soul for a while. Those are not delusions, you should get better equipment to study the human body when scanning for truths.

  29. I've lost many loved ones and related to his quote "Depression is aggression turned inward." I'm coming out to the other side healing and moving on.

  30. Capitalism has always been the elephant in the room when it comes to mental illness. Living paycheck to paycheck causes anxiety. Not being able to see a doctor is stressful. Choosing between paying rent or having heat/electricity feels hopeless. Working multiple jobs and never being able to see our loved ones is depressing. Laboring for a wage is alienating. Marketing ourselves to capitalists for jobs that determine our worth as human beings is insulting… capitalist life is a meaningless grind for most of us. It's no wonder we're all depressed.

  31. It seems like many people say that the journey out of depression involves many different things. I've heard several people say they do a combination of psychotherapy, antidepressant, meditation, and some cope by exercise, support groups and practising their faith. I wish there were as many free support groups for people struggling with depression as there are AA groups! I have two friends who struggle with depression and they do not have insurance to see a mental health professional. So their health needs go untreated. That is so sad!

  32. Based on a hypothesis that mental illness is a biological disease there is 40 billion dollars a year in sales of psychiatric medications in the U.S. 1/4 of Canadian women take an antidepressant. 1/5 of Americans take a psychiatric medication. 1/2 of foster children are being chemically lobotomized for control and profit. I can't imagine a more diabolical form of child abuse than disempowering a child by telling them they have something wrong with their brain and can't control their behaviour unless they take a drug. Long term use of Ritalin has shown to cause a 10% shrinkage in brain mass and stunted growth as much as 2". 1/9?? American boys is being treated for ADHD. The U.S. uses 90% of the world's Ritialin. The are no biological tests or imaging of any kind that can validate any mental disorder as a disease. Quick someone call WHO there's an epidemic of chemically unbalanced people in North America! https://youtu.be/Ep1ODxCoYlI

  33. https://youtu.be/W4Xb29geVwE. I took psychiatric medications for 10 years and they caused me to think and behave in ways that were contrary to my core values, I will never touch them again. Drugs don't change your reality only your perception of it. There are 'Black Box' warnings for a reason! I needed to deal with my issues of childhood abuse, foster care and the resulting alcoholism, depression, anxiety and self destructive behaviour, it wasn't a fucking disease that could be cured by a pill. I believe that it is a crime against humanity to disempower people by leading them to believe their issues are a biological disease that need medication to correct but offer no evidence to the patient to support that claim. This is a profitable lie and 87% of Americans believe this to be a truth!

  34. “The whole educational and professional training system is a very elaborate filter, which just weeds out people who are too independent, and who think for themselves, and who don’t know how to be submissive, and so on — because they’re dysfunctional to the institutions.” – Noam Chomsky. Psychiatry is a corporate lackey for 'Big Pharma'.

  35. "Come on pull yourself together", (no one says that) I was suicidal, it's not a matter of pulling ones self together, it's about the support of good minded people and not people that will lead you to believe you have a disease i.e. you are a helpless victim of a brain disease and need drugs to treat that disease, just like insulin for diabetes. Prove it! All the symptoms of the various levels of depression are described but what biological evidence is used to determine that even the most depressed patient actually has a DISEASE? 40 billion dollars a year in sales of psychiatric drugs in the U.S.! Having attempted suicide and being hospitalized I would never suggest a person experiencing psychiatric disturbances isn't suffering, however with my life experiences as a 64 year old woman and my observations of people I have known throughout my life, I no longer believe the B.S. Psychiatry is spewing and we are supposed to lap it up like its being given to us by some infallible God. Pharmaceutical companies are one of the most corrupt corporations on the planet, ghost written articles, cherry picked studies, paid corporate lackeys. Pharmaceutical corporations have paid billions of dollars in fines for fraud, damages etc. Dr. Peter Breggin has testified in cases and patients were awarded for the damage caused by these mind altering, brain damaging neurotoxins. It's my understanding that studies have shown even the most depressed patients will recover after about 14 months but long term use of medications will cause a chronicity of symptoms. "The worse thing you can do to a damaged person is damage them more" – Dr. Peter Breggin

  36. Didn't Van Gogh appreciate sunsets? Didn't Rothko? In my experience what depression does is this – you appreciate sunsets but they no longer provide consolation from your sense of despair. Read more poetry, man; experience more Art. And, for the record, his dualist approach is reductive. There are far fewer differences between the two forms of the disorder, and to suggest otherwise went out of fashion (certainly here in the UK) way back in the 1980s when I trained as a mental health professional.

  37. “In truth, the ‘chemical imbalance’ notion was always a kind of urban legend- – never a theory seriously propounded by well-informed psychiatrists.” Dr. Ronald Pies – July 11, 2011 in Psychiatric Times

    We have hunted for a big simple neurochemical explanations for psychiatric disorders and have not found them. – Kenneth Kendler, Psychological Medicine, 2005

  38. Three years ago Canada passed the 'Assisted dying law', and even before it was passed news articles were appearing suggesting that people with mental health issues should have this right as well. These articles were accompanied by personal stories. The articles also pointed out that this is already being done in Europe, accompanied by a personal story as well. In 1939 Nazi Germany 100 thousand hospitalized mental health patients were sent to the gas chambers based on the hypothesis that these people were biologically and genetically damaged. The slippery slope!

  39. The american school about depression is wrong. Give them drugs because is just a biological disorder. But they don’t stress the importance of society and symbolism and the the other things that make as be human not 🐀 in a laboratory.

    Carl Gustav Jung approach and humanistic approach of French school treating the depression is much more effective. You can heal yourself without pills or drugs. The body and mind is not a static chemical thing. We are not just hormones and dopamine.

  40. "There will be, in the next generation or so, a pharmacological method of making people love their servitude, and producing dictatorship without tears, so to speak, producing a kind of painless concentration camp for entire societies, so that people will in fact have their liberties taken away from them, but will rather enjoy it, because they will be distracted from any desire to rebel by propaganda or brainwashing, or brainwashing enhanced by pharmacological methods. And this seems to be the final revolution." Aldous Huxley

  41. I'm a soon to be homeless again disabled diabetic with a thyroid condition and depression is the hardest thing I've ever admitted to and the hardest to battle. Psych drugs nor therapy has never worked.

  42. I have a feeling in the less developed low income countries depression is not so common. I'm staying in Nigeria and many people went through poverty and trauma but people seem to be cheerful all the time. Is this because things like they are devoted believers or just those depressed are not under the spot light?

  43. th 40th minute packs as much perspective as 1000 pages by Laurence Rickels (but if you like wordplay pun portmanteau and swushcracking your way thru dried and brittle pundergrowth with a big neologishtick, do both)

  44. If anyone has got depression There is nothing wrong with you. If you don't have depression you got to be Heartless Soulless mindless Zombie or deaf and blind . . You want to know about human behaviour go chat up another mans girl when he's at the bar . Give a cop all the verbal abuse you can when there's no witnesses screw your partners family go show you got 10 grand to a prostitute or nearly anyone who doesn't I am saying you learn more about human behaviour looking around you than listening to somebody who thinks he can put it all in a nutshell . Take 1 Breath and feel the life and in it you can find all the knowledge you don't need to know.

  45. I think I have had depression since childhood and yes there were good years in between but somehow or the other I have a tendency to go back into it again. It seems my life's most productive years were taken from me where I could have had the energy to devote to a particular career path I wanted for myself. Instead I went from one thing to the other, and ultimately ending in a depressed/disabled condition for years together. I can't take stressful events, even the minor ones. As a result and it would be unbelievable for some: I have never had a job in life and I am in early 30s now. Not that there were no opportunities, but the kind of jobs which I was hoping for, I could never get to them. Most of my life I have been lying at one corner of my home, in my bed, unable to explain to others what I do or why I have been living like that or why don't I work. Even I don't know. For 2-3 years in between when I was fine and magically had all the energy to get out of bed, I was always afraid that my depression might return someday and I never want to go back to that state. It returned again and much worse indeed. I suffer and suffer daily and even though I live with this condition since good 16-17 years, and know how it makes me feel, I have not been able to manage it or do away with it. My point is that the hopelessness and suffering doesn't come down with years of experience. It's still the same. There are physical symptoms of depression on me and nobody around me can even tell if I am suffering. Even my parents refuse to acknowledge my depression. They feel I don't work hard or try, they feel I am mentally weak that's why I have those feelings. Hence I have never taken any medication or therapy for it, and only once on my insistence I went to the doctor which was as apathetic as anything. Honestly I have seen friends take medication and therapy for it, but never saw them get better. Infact they turned out much worse than they were before. Before treatment people could not have been able to make out that they were depressed or anything but after treatment people could definitely make out that this person is crazy or abnormal. The culprit was medication and therapy. So as much as I would love to be inspired by this person's lecture and seek treatment, I'd rather stay where I am, hoping for some miracle or as in past experience some good 2-3 years in between the onset of another phase. Let's face it many of us will only be able to afford a kind of doctor or healthcare which is miles away from the ideal, empathetic lab environments of Stanford or other such places. So I won't waste my time even thinking of going. Now at this point I question myself that if I am going to suffer all along like that because miracles don't really happen and good (depression-free) phases of life end and then again long depression awaits my life, so why don't I end my life right now so that I can reduce so much suffering, myself and yes even people around you get affected by your depression, just like people do when they get terminally ill, get euthanized. I don't have the answer to why I have still not killed myself or tried to kill myself in almost a decade. It's perhaps because of the overall beauty and charm of life, new unexpected relationships, new experiences, it's like one door closed but two doors opened, different perspectives gained or maybe plain simple lethargy to act.

  46. Law, medical, and nursing students I address you in hopes of change to come. There has been an injustice and lack of duty around patient care for decades that needs to be addressed on many fronts. It is the issue of harm from the procedure called electroshock.

    Performed at leading hospitals to include HMO Kaiser Permanente. Procedure delivers up to 450 volts to the brain and greater. No FDA testing for safety or even effectiveness. No pre-market approval ever done on devices before the FDA. This involves decades of neglect around a protected population under the ADA. This also involves fraud at best by insurers that pay out billions annually on this unproven and untested procedure. Then the government often pays out a lifetime of disability payments secondary to TBI outcomes all aware of at miniumum.

    This is not only fraud and discrimination.

    Used to be used only for severe depression, now used for many issues. Used on our children, Veterans, and even women in pregnancy. This is harm and cover ups in the billions annually in US alone.

    California courts have recently proven brain injuries at minimum from this procedure around a national product liability suit currently taking place. Electrical trauma impacts all bodily systems with damages that can evolve years out. Damages to evolve include CTE, ALS, and cardiac issues etc. Consent mentions only temporary memory loss expected to resolve in six weeks and the typical anesthesia risks. We are not warned of actual structural brain changes that result from this documented in their own research. We are not warned that bilateral ECT impacts our brain stems where our vital functions exist such as blood pressure and heart rate.

    There are medical malpractice firms also interviewing for suits around damages and two suits filed against the FDA. FDA recently declassified from experimental class to that of class 2 without any testing done before this lowering of classification. They also lowered this with an active lawsuit in place showing damages around devices. They do not test because even a layman would anticipate these damages with thought and many would be held accountable.

    Law students your material risk of brain injury for starters missing from consents for medical malpractice. This is purely trauma. All trauma is based on MECHANISM. You have a known mechanism such as blunt force with the NFL injuries and you then have anticipated and known outcomes based on this. In our population it is electrical so you have a known and anticipated outcomes in ALL populations according to trauma medicine, to include those with mental health histories. This is impacting professionals now who are unable to resume their professions secondary to brain injuries from this. This includes, teachers, attorneys, doctors, nurses. We need representation to address these damages. Please write the papers around this and ask the questions in your clinicals. Doctors take an oath and are failing criminally to warn, protect, and not cause harm. You are now aware of this situation and problem and I ask you to act. Thank you. Please see ectjustice now owned by law firms participating in national product liability suit. If you have information to contribute to law firms around this please contact the DK law group.

  47. This lecture made me realize that my bouts of depression isn't so bad compared to some others. To whomever is struggling out there: set & accomplish goals + manage stress/remove primary life stressors. That's all it really takes to get yourself out of a funk, but it takes a lot of work.

  48. Over complication, too much science. Depression is a signal that you have needs that arent being met, whether they be emotional, physical, or psychological. Taking pills is not a substitute for an unfulfilling life; you need to actually change your life, which is very difficult to do when suffering from the motor impairment that comes with major depression. Just taking a shower or doing a load of laundry is mentally and physically exhausting for me.

  49. I'm having trouble believing it's a biochemical disorder. What about existential depression? Especially those who are more susceptible to it?

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